Phenylpropanoids and polyketides
Selleck Chemical LLC Daunorubicin HCl S3035-50mg
Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0 02 M in a cell-free assay Daunorubicin is a topoisomerase II inhibitor that induces apoptosis Daunorubicin (RP 13057) HCl can be used to induce animal models of Kidney Disease
Medchemexpress LLC 3-Hydroxy-7-methoxyflavone | 7478-60-6 | 99.4% | 268.26 | 5 MG
3-Hydroxy-7-methoxyflavone is a flavonoid isolated from natural Salvia elegans, known for its anti-anxiety effects. This compound is for research use only.
- Isolated from natural Salvia elegans.
- Exhibits anti-anxiety effects.
- Cytotoxicity against human KB cells with an ED50 of 26 µg/mL.
- Recommended storage at room temperature for 3 years, or in solvent at -80°C for 2 years or -20°C for 1 year.
- Soluble in DMSO at 50 mg/mL.
Cayman Chemical MetronIdazole Benzoate 1g
An antibiotic and antiprotozoal agent; active against P. asaccharolyticus, C. perfringens, C. septicum, B. fragilis, and B. thetaiotaomicron (MICs = 3.6, 7.3, 1.8, 7.3, and 7.3 µM, respectively); reduces parasitemia in rats when cultured with T. congolense or T. brucei prior to infection
Cayman Chemical 3-Cyno-7-ethoxycoumarIn 10mg
A fluorogenic CYP450 substrate; a substrate for CYP1A1 and CYP1A2; metabolized to a lesser extent by CYP2D6 and CYP2C19; metabolized to 3-cyano-7-hydroxycoumarin and its fluorescence can be used to quantify CYP450 isoform activity
Medchemexpress LLC HY-N0610 100mg Medchemexpress, trans-Cinnamic acid CAS:140-10-3 Purity:>98%
Medchemexpress, HY-N0610 100mg trans-Cinnamic acid CAS:140-10-3 trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1 [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical LuteolIn 7-O-GlucuronIde 10mg
A flavonoid with antioxidant, enzyme inhibitory, and anti-inflammatory properties; scavenges DPPH radicals in a cell-free assay (IC50 = 80.6 μM); inhibits porcine α-amylase and yeast α-glucosidase in vitro (IC50s = 61.5 and 14.7 μM, respectively); inhibits rat aldose reductase in vitro (IC50 = 0.7 μM) and sorbitol accumulation in isolated rat lens at 5 μg/ml; inhibits LPS-induced cytokine release from RAW 264.7 macrophages in a dose-dependent manner
Selleck Chemical LLC 4-Hydroxycyclohexanecarboxylic
trans-4-Hydroxycyclohexanecarboxylic acid is used as an organic intermediate
Cayman Chemical Tangeretin Neurochemicals
A polymethoxylated flavone isolated from citrus peels; inhibits signaling in cancer cells, reducing ERK signaling in T47D breast cancer cells (IC50 ~3 μM)
Cayman Chemical EpIcatechIn Galate 25mg
A natural catechin which inhibits the growth of cancer cells and has anti-inflammatory effects; has potent antioxidant activity and facilitates the killing of methicillin-resistant strains of S. aureus
Medchemexpress LLC (-)-Epigallocatechin-3-O-(4-O-methyl)gallate | 224434-07-5 | MFCD06799453 | 472.40 | 1 MG
(-)-Epigallocatechin-3-O-(4-O-methyl)gallate is an orally active catechin derivative found in Taiwanese oolong tea. It can inhibit histamine release and exhibits anti-inflammation and anti-allergic effect. It can be used for researches of immunology and inflammation, such as type I allergic.
- Inhibits histamine release from IgE/antigen-activated mouse mast cells (45% inhibition rate at 50 μg/mL).
- Exhibits excellent plasma stability (only 10% degradation rate at 500 μg/mL for 15 mins).
- Significantly inhibits type I allergic reactions in mice sensitized with ovalbumin (5-50 mg/kg, i.g.).
- Achieved approximately 50% inhibition rate of abdominal wall blue dye permeation at 10 mg/kg in animal models.
Indofine Chemical Linarin With Hplc, 5 Mg
LINARIN with HPLC, Flavonoid & Coumarins, 480-36-4, 98.5% by HPLC, 5 mg
Medchemexpress LLC Myricetin | 529-44-2 | C15H10O8 | 200 MG
Myricetin is a plant-derived flavonoid known for its strong antioxidant, anticancer, antidiabetic, and anti-inflammatory properties. It exhibits diverse cellular effects, including radical scavenging activity and the ability to modulate various signaling pathways, making it suitable for a wide range of research applications.
- Exhibits scavenging activity against various radicals and ions.
- Prevents cancer cell death by apoptosis through regulation of PI3K/Akt and MAPK signaling pathways.
- Displays antiphotoaging effects by quenching free radicals in the skin and suppressing UVB-induced COX-2 expression.
- Inhibits human Hsp70 with notable IC50 values.
- Causes inhibition of rabbit platelet aggregation induced by ADP, arachidonic acid, collagen, and PAF.
Cayman Chemical 3-Cyno-7-ethoxycoumarIn 25mg
A fluorogenic CYP450 substrate; a substrate for CYP1A1 and CYP1A2; metabolized to a lesser extent by CYP2D6 and CYP2C19; metabolized to 3-cyano-7-hydroxycoumarin and its fluorescence can be used to quantify CYP450 isoform activity
Cayman Chemical Apigenin Inhibitors
Inhibits CK2 activity in the renal cortex with an IC50 value of 30 µM; potent inhibitor of NO and PGE2 biosynthesis by reducing iNOS and COX-2 expression
Cayman Chemical EpIcatechIn Galate 10mg
A natural catechin which inhibits the growth of cancer cells and has anti-inflammatory effects; has potent antioxidant activity and facilitates the killing of methicillin-resistant strains of S. aureus